Volume 8, Issue 4 (Oct-Dec 2019)                   JCHR 2019, 8(4): 228-236 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Malekinezhad H, Moflehi D, Abbasi H, Behzadi A. Effect of low or high volume of high-intensity interval training protocols on the Leptin and lipid profile in men with type 2 diabetes. JCHR. 2019; 8 (4) :228-236
URL: http://jhr.ssu.ac.ir/article-1-527-en.html
1- 1. Department of Physical Education and Sport Sciences. Shahid Bahonar University of Kerman. Kerman, Iran
2- 2. Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, Shahid Bahonar University of Kerman, Kerman, Iran
3- 3. Department of Sport Sciences, Faculty of Psychology, Yazd University, Yazd, Iran , habbassi@yazd.ac.ir
Abstract:   (726 Views)
Introduction: Sport activity leads to metabolic and physiological adaptations, which may have a beneficial role for diabetic patients. The purpose of this study was to compare the effects of low volume and high volume high-intensity interval training (HIIT) on serum leptin and some of the lipid profiles of type 2 diabetic men.
Methods: In this randomized clinical trial, 30 males with type 2 diabetes mellitus were divided into three groups of 10, including low volume and high volume HIIT and control groups. The low volume groups underwent intensive training for up to two minutes and a high volume group up to six minutes for 8 weeks. Blood lipid profile indicators were measured before and 48 hours after the last exercise session. By using SPSS version 25, the paired t-test, ANOVA, ANCOVA and LSD as a post hoc test were used to analyze the data. For all analysis α=0.05 was considered as the level of statistical significance.
Results: There was a significant difference before and after 8 weeks of low-volume HIIT training at triglyceride (p = 0.049). However, there was no significant difference in serum leptin, cholesterol, LDL-C, and HDL-C in men with type 2 diabetes (p>0.05). ANCOVA only found a differences between groups on BMI (F2, 26 = 3.61, p = 0.041). Also, the post hoc in two by two comparisons of HDL showed that there was a significant difference between high volume HIIT and control groups (p = 0.021) and low volume and control group (p = 0.011). The HDL-C levels in HIIT training groups increased significantly compared to controls.
Discussion: Considering other proven adaptations of HIIT training on triglyceride, HDL and improving glycemic indexes is a useful and safe training for type 2 diabetic patients. Therefore, needing a very short time for this training, metabolic, functional and physiological adaptations of HIIT training, along with other exercises are recommended to improve the condition and reduce the risk of cardiovascular disease and complications of type 2 diabetes.
Full-Text [PDF 781 kb]   (232 Downloads) |   |   Full-Text (HTML)  (24 Views)  
Review: Research | Subject: General
Received: 2019/05/13 | Accepted: 2019/12/29 | Published: 2019/12/29

References
1. Abou-Seif MA, Youssef AA. Evaluation of some biochemical changes in diabetic patients. Clinica Chimica Acta. 2004;346(2):161-70. [DOI:10.1016/j.cccn.2004.03.030]
2. World Health Organization. Diabetes. 2018. Available from: www.who.int/news-room/facts-in-pictures/detail/ diabetes
3. Asgari M, Mohammadi M. Diabetes bus: benefits and difficulties: letters to the editor. Tehran University Medical Journal TUMS Publications. 2018;75(11):848.[persion]
4. Morovati SM, Rouhani TN. Perceived self-efficacy in self-care behaviors among diabetic patients referring to Yazd Diabetes Research Center. Journal of Birjand University of Medical Sciences. 2009 ; 15(4) : 91-99.[persion]
5. Franz MJ, Bantle JP, Beebe CA, et al. Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications. Diabetes care. 2002 ; 25(1): 148-98. [DOI:10.2337/diacare.25.1.148]
6. Stamler J, Vaccaro O, Neaton JD, et al. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes care. 1993; 16(2): 434-444. [DOI:10.2337/diacare.16.2.434]
7. Javadi E, Yarahmadi S, Larijani B, et al. Prevalence of dyslipidaemia in diabetic patients attending the diabetes clinic at doctor shariati university hospital between october 1998 and september 2000. Journal of Diabetes and Metabolic Disorders. 2002;1:28.
8. Meier U, Gressner AM. Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin. Clinical Chemistry. 2004; 50(9): 1511-25. [DOI:10.1373/clinchem.2004.032482]
9. Ookuma M, Ookuma K, York DA. Effects of leptin on insulin secretion from isolated rat pancreatic islets. Diabetes. 1998; 47(2): 219-23. [DOI:10.2337/diab.47.2.219]
10. Bouassida A, Chamari K, Zaouali M, et al. Review on leptin and adiponectin responses and adaptations to acute and chronic exercise. British journal of sports medicine. 2010; 44(9): 620-30. [DOI:10.1136/bjsm.2008.046151]
11. Azarbayejani M. The effects of a single session of combined aerobic and resistance exercise on leptin levels and insulin resistance index in sedentary men. Qom University of Medical Sciences Journal.2012; 6(1):46-54.
12. Koga S, Kojima A, Ishikawa C, et al. Effects of diet-induced obesity and voluntary exercise in a tauopathy mouse model: implications of persistent hyperleptinemia and enhanced astrocytic leptin receptor expression. Neurobiology of disease. 2014; 71:180-92. [DOI:10.1016/j.nbd.2014.08.015]
13. Sari R, Balci MK, Balci N, et al. Acute effect of exercise on plasma leptin level and insulin resistance in obese women with stable caloric intake. Endocrine research. 2007; 32(1-2): 9-17. [DOI:10.1080/07435800701670070]
14. Ahmadizad S, Ghorbani S, Ghasemikaram M, et al. Effects of short-term nonperiodized, linear periodized and daily undulating periodized resistance training on plasma adiponectin, leptin and insulin resistance. Clinical biochemistry. 2014; 47(6): 417-22. [DOI:10.1016/j.clinbiochem.2013.12.019]
15. Racil G, Coquart JB, Elmontassar W, et al. Greater effects of high-compared with moderate-intensity interval training on cardio-metabolic variables, blood leptin concentration and ratings of perceived exertion in obese adolescent females. Biology of sport. 2016; 33(2): 145. [DOI:10.5604/20831862.1198633]
16. Avazpor S, Kalkhoran JF, Amini HA. Effect of 8 weeks of high intensity interval training on plasma levels of adiponectin and leptin in overweight nurses. Novelty in Biomedicine. 2016;4(3):87-92.
17. Soori R, Rezaeian N, Salehian O. Effects of interval training on leptin and hormone levels affecting lipid metabolism in young obese/overweight men. Iranian Journal of Endocrinology And Metabolism (IJEM) 2012: 14(3) 248-256.[persion].
18. Caldeira RS, Panissa VL, Inoue DS, et al. Impact to short-term high intensity intermittent training on different storages of body fat, leptin and soluble leptin receptor levels in physically active non-obese men: A pilot investigation. Clinical nutrition ESPEN. 2018;28:186-92. [DOI:10.1016/j.clnesp.2018.08.005]
19. ZilaeiBouri S, Khedri A, ZilaeiBouri M. Comparing the effects of aerobic exercises of high and moderate intensity on serum leptin levels and capacity of fat oxidation among young obese girls. Journal of Fasa University of Medical Sciences. 2013; 3(1): 81-7.
20. Kong Z, Sun S, Liu M, et al. Short-term high-intensity interval training on body composition and blood glucose in overweight and obese young women. Journal of diabetes research. 2016;2016: 1-9. [DOI:10.1155/2016/4073618]
21. Whyte LJ, Gill JM, Cathcart AJ. Effect of 2 weeks of sprint interval training on health-related outcomes in sedentary overweight/obese men. Metabolism. 2010; 59(10): 1421-8. [DOI:10.1016/j.metabol.2010.01.002]
22. Gharai Arefi R, Hematifar M, Kordi M, R. The effect of a high intensity interval training program on lipid profile in sedentary young men. Journal of sport Biosciences, 2014; 6(3): 259-272.[persion].
23. Nourshahi N, Karimi Z, Ghane Basiri M, et al. Dietary patterns and risk of lipid disorders in patients with type 2 diabetes. Razi Journal of Medical Sciences. 2015; 21(128): 72-84.[persion].
24. Kraus WE, Houmard JA, Duscha BD, et al. Effects of the amount and intensity of exercise on plasma lipoproteins. New England Journal of Medicine. 2002; 347(19): 1483-92. [DOI:10.1056/NEJMoa020194]
25. shahidi F, pirhadi S. The effect of physical exercise and training on serum leptin levels. 2014; 21(1256): 1-14. [Persian]
26. Pourvaghar MJ, Bahram ME, Sayyah M, et al. The Effects of Three Months of HIIT on Plasma Adiponectin on Overweight College Men. International Journal of Sport and Health Sciences. 2017; 11(8): 448-51.

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


© 2020 All Rights Reserved | Journal of Community Health Research

Designed & Developed by : Yektaweb