en اپیدمیولوژی Epidemiology مروری Review <div style="text-align: justify;"><span style="font-size:12px;"><span style="font-family:Times New Roman;"><span style="line-height:115%"><b><span style="line-height:115%">Abstract<i>:&nbsp; </i></span></b><span style="line-height:115%">Human Monkeypox is a zoonotic disease caused</span><span lang="EN-GB"><span style="line-height:115%"> by</span></span><span style="line-height:115%"> 2 distinct clades of human monkeypox virus (MPXV). MPXV infections can cause several clinical symptoms including fever, skin rash, back pain, and lymphadenopathy in humans. Even though MPXV infections are generally self-limiting, death is possible and fatality due to MPXV infections in humans is 3-6 percent. While the disease is endemic to Africa, its potential to cause outbreaks in other continents has been observed. The natural reservoir of MPXV in Africa and the full host range of the virus are not known, but rodents are suggested to be the reservoirs. The transmission of MPXV occurs via close contact and the prevention strategies include avoiding close contact and post-exposure prophylactic vaccination of people at risk with smallpox vaccines. In this study, the most recent information about the epidemiology of MPXV about the latest research on the 2022 outbreak of MPXV has been reviewed. </span></span></span></span><br> &nbsp;</div> Monkeypox, Monkeypoxvirus, epidemiology, zoonoses 140 148 http://jhr.ssu.ac.ir/browse.php?a_code=A-10-2034-1&slc_lang=en&sid=1 Aliasghar Fakhri-Demeshghieh aliasghar.fakhri@ut.ac.ir 0000-0003-1693-533X No Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Hesameddin Akbarein akbarein@ut.ac.ir 0000-0003-3276-4649 Yes Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Parsa Almasi parsa.almasi@ut.ac.ir 0000-0002-4901-2470 No Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran